• Matthijs de Ligt is ruled out of the Athletic Club and West Ham matches due to a muscle injury picked up against Brentford.
• Ruben Amorim expresses concern over De Ligt's injury, particularly regarding its impact on squad depth for upcoming games and the next season.
• Manchester United leads Athletic Club 3-0 in the Europa League semi-final but faces challenges with multiple players sidelined due to injuries.

Manchester United is facing an injury crisis ahead of their Europa League semi-final second leg against Athletic Club and a Premier League match against West Ham United. Key defender Matthijs de Ligt sustained a muscle injury during the match against Brentford and has been ruled out for both games. This injury compounds existing concerns, with other players also sidelined. Despite leading Athletic Club 3-0 from the first leg, manager Ruben Amorim has warned against complacency, emphasizing the importance of securing a win at Old Trafford. The team's ability to cope with these absences will be crucial for their Europa League aspirations and domestic form.

• What: Matthijs de Ligt suffered a muscle injury during Manchester United's match against Brentford, sidelining him for upcoming games.
• Who: Matthijs de Ligt, Ruben Amorim, Manchester United, Athletic Club, West Ham United, Ayden Heaven, Toby Collyer, Lisandro Martinez, Diogo Dalot, Joshua Zirkzee, Harry Maguire, Luke Shaw, Amad Diallo, Noussair Mazraoui, Christian Eriksen, Casemiro, Bruno Fernandes.
• When: Injury occurred on May 4, 2025, during the match against Brentford. De Ligt will miss the Europa League semi-final second leg on May 8, 2025, and the match against West Ham on May 11, 2025.
• Where: Old Trafford (Manchester, England) for the Europa League semi-final second leg and the Premier League match against West Ham United.

The injury to Matthijs de Ligt presents a significant setback for Manchester United, impacting their defensive stability and squad depth. With other key players already sidelined, Ruben Amorim faces a challenge in managing the team's resources across both the Europa League and Premier League campaigns. The manager's concern, as highlighted in multiple sources, underscores the importance of De Ligt to the team. Despite holding a significant lead in the Europa League semi-final, the team cannot afford complacency, especially given their inconsistent form. The situation also raises questions about the team's long-term strategy and their ability to cope with injuries.

I don’t know so I’m really concerned [but] not about Thursday. We took off Luke Shaw at half-time to protect [him] and have players for Thursday, but I’m more concerned whether it is a small or big injury [for De Ligt] and thinking about next season.

It is not a big issue, that is the good thing. He cannot play tomorrow or Sunday (against West Ham United) but then we will check day by day.

That is clear, if you look at our season, anything is possible. We have to understand one goal can change anything, the momentum of the game, one sending off, you saw it a week ago. We are fighting to win the game. We are thinking about winning the game.

Matthijs de Ligt's injury has added to Manchester United's existing injury woes, creating uncertainty for the team as they approach a crucial Europa League semi-final and a Premier League fixture. Despite a comfortable lead from the first leg, the team must remain focused and adapt to the absence of key players. The manager's concern reflects the potential impact on both short-term results and long-term planning. The team's performance in the upcoming matches will be a test of their resilience and tactical adaptability.